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Recent Advances in the Synthesis of Well-Defined Glycopolymers.

De novo mutation (French : mutation de novo, néo-mutation) Spontaneously occurring mutation.

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ConCept: de Novo Design of Synthetic Receptors for Targeted Ligands.

1961, 83, 3080) made the first total synthesis of arachidonic acid.

Imai J demonstrated that the oxidative desaturation of a saturated fatty acid (palmitic acid) is depressed in diabetic rats ().

Kennedy EP described the general pathways of the glycerolipid biosynthesis in animal cells ().

Bremer J et al.

Living Radical Polymerization as a Tool for the Synthesis of Polymer-Protein/Peptide Bioconjugates.

first described the presence of monogalactosyl diacylglycerol inan animal tissue, the bovine brain ().

A sulfonated glycolipid (sulfoquinovosyl diacylglycerol) was discovered in thegreen alga ().

K., Chromophore-supported purification in parallel synthesis.

A Chemoselective Approach for the Accelerated Synthesis of Well-defined Dendritic Architectures.

demonstrated that nearly allphosphatidylserine and a minimum of 70% of phosphatidylethanolamine is on theinside surface of the human erythrocyte membrane, thus "presenting a strongevidence for an asymmetric arrangement of phospholipids" ().

First demonstration of an inhibition of sterol biosynthesis (HMG-CoA reductaseactivity) by oxygenated derivatives of cholesterol in cultured mammalian cells ().

For the first time, the existence of polyunsaturated fatty acids was reported inmarine bacteria ().

(French : code génétique) The sequence of nucleotides, coded in triplets (codons) along the mRNA, that determines the sequence of amino acids in protein synthesis. The DNA sequence of a gene can be used to predict the mRNA sequence, and the genetic code can in turn be used to predict the amino acid sequence.

Pathways for ceramide synthesis

J., Synthesis of hydrogels with well defined network structure using click chemistry.

I have been at the Cavendish since 1983, and became a professor in 1998. My activity sits within the sector of Biological and Soft Systems, and focusses on using the ideas of soft matter physics to study a wide range of systems of both synthetic and biological origin. There is an emphasis on using different types of microscopy, and in particular environmental scanning electron microscopy, but these are by no means the only approaches used. We have recently been developing passive microrheological techniques for the study of a range of complex fluids, including the inside of cells; we are exploring cell adhesion, mitosis and spreading using optical approaches (including the effect of external physical cues such as topographical patterns); and we have a substantial effort directed at protein aggregation at intermediate lengthscales, predominantly using model protein systems including beta lactoglobulin and insulin but extending to A beta. The unifying theme is understanding structure-function-processing relationships. My group comes from a diverse range of backgrounds, as does my funding.

Virus (French : virus) A noncellular biological entity that can reproduce only within a host cell. Viruses consist of nucleic acid covered by protein; some animal viruses are also surrounded by membrane. Inside the infected cell, the virus uses the synthetic capability of the host to produce progeny virus.

J., Synthesis of well-defined hydrogel networks using Click chemistry.
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  • De novo synthesis of complex molecules from simple molecules ..

    obtained evidence that fatty acids aresynthesized in mice and rats by condensation of acetic acid ().

  • De novo biosynthesis of secondary metabolism enzymes …

    Syntheses of Hemoprotein Models that can be Covalently Attached onto Electrode Surfaces by Click Chemistry.

  • PDNS - Purine de Novo Synthesis (gene) | AcronymFinder

    M., Synthesis of bio-inspired hybrid polymers using peptide synthesis and protein engineering.

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and that synthesized de novo, ..

R., Activity-Based Protein Profiling Reagents for Protein Arginine Deaminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently Labeled Probe.

De novo lipogenesis during controlled overfeeding with sucrose or ..

R.; Lober, S.; Hubner, H.; Gmeiner, P., Click chemistry on solid phase: parallel synthesis of -benzyltriazole carboxamides as super-potent G-protein coupled receptor ligands.

De novo synthesis of phosphorylated tri-block …

Sequence untranslated (French : séquence non traduite) A region of mRNA that is not used in the synthesis of an amino acids sequence of a given peptide or protein. They usually appear at either end of the sequence that codes for the amino acid sequence.

De novo synthesis of phosphorylated tri-block copolymers with ..

B., Synthesis of azide-alkyne fragments for click' chemical applications; formation of oligomers from orthogonally protected trialkylsilyl-propargyl azides and propargyl alcohols.

Our results suggest that purine de novo synthesis is a limiting ..

Ribonucleic acid, RNA (French : acide ribonucléique, ARN) A chemical found in the nucleus and cytoplasm of cells; it plays an important role in protein synthesis and other chemical activities of the cell. The structure of RNA is similar to that of DNA. There are several classes of RNA molecules, including messenger RNA, transfer RNA, ribosomal RNA, and other small RNAs, each serving a different purpose.

what does de novo mean in biology/Evindex …

Polymerase, DNA or RNA (French : polymérase, ADN ou ARN) Enzymes that catalyze the synthesis of nucleic acids on preexisting nucleic acid templates, assembling RNA from ribonucleotides or DNA from deoxyribonucleotides.

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