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DNA Synthesis, Mitosis, Meiosis - Pysiology ..

Interphase of the cell cycle, including G₁, S, and G₂ phases. How the cell replicates its DNA before mitosis.

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DNA synthesis and mitosis in erythropoietic cells

produces two daughter cells that are genetically identical to each other, and to the parental cell. A diploid cell starts with 2N chromosomes and 2X DNA content. After DNA replication, the cells is still genetically diploid (2N chromosome number), but has 4X DNA content because each chromosome has replicated its DNA. Each chromosome now consists of a joined pair of identical sister chromatids. During mitosis the sister chromatids separate and go to opposite ends of the dividing cell. Mitosis ends with 2 identical cells, each with 2N chromosomes and 2X DNA content. All eukaryotic cells replicate via mitosis, except germline cells that undergo meiosis (see below) to produce gametes (eggs and sperm).

18/12/2017 · DNA synthesis and mi..

Chromosomes by definition contain the DNA that makes up the fundamental genome of the cell. In a prokaryote, the genome is usually packaged into one circular chromosome consisting of a circular DNA molecule of a few million base pairs (Mbp). In eukaryotes, the genome is packaged into multiple linear chromosomes, each consisting of a linear DNA molecule of tens or hundreds of Mbp. Chromosomes exist at all different phases of the cell cycle. They condense and become visible to light microscopy in prophase of mitosis or meiosis, and they decondense during interphase, in the form of chromatin (DNA wrapped around nucleosomes, like “beads on a string”).

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Chromosomes condense and become visible by light microscopy as eukaryotic cells enter mitosis or meiosis. During interphase (G1 + S + G2), chromosomes are fully or partially decondensed, in the form of chromatin, which consists of DNA wound around histone proteins (nucleosomes).

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